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Applications
Technical Documents
Publish Date | Press Release |
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02/07/2023 | Phenomenex – Today’s Biopharma Focus for Tomorrow’s Better World |
Publish Date | Press Release |
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08/23/2021 | Phenomenex Introduces New Biozen dSEC LC Columns |
06/17/2021 | Phenomenex Introduces NEW SINGLE GC Solution for Dioxin Analysis |
04/05/2021 | Phenomenex Announces Direct Sales and Support within Indonesia |
03/08/2021 | Phenomenex Expands Novum Product Line with Novum PRO SLE |
02/22/2021 | NEW bioZen Nano LC Columns |
Torrance, Calif. (June 17th, 2019) - Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces the Kinetex 2.6 µm PS C18 - the eleventh selectivity in the Kinetex core-shell HPLC/UHPLC family. The new core-shell PS C18 phase is beneficial for all types of compounds (acids, bases, neutrals), but especially for the analysis of polar basic compounds. The phase has demonstrated increased polar analyte retention, improved peak shape for troublesome basic analytes under typical reversed phase conditions, and a unique multi-modal interaction selectivity making it indispensable tool for multi-compound and metabolite profile screens.
The Kinetex core-shell (superficially porous) particle technology delivers higher efficiency (N) and performance compared to columns packed with fully porous particles. In addition, the Kinetex core-shell manufacturing process allows for greater control of the overall average particle diameter, lending to greater monodispersed particle packing. The consistency of particle diameter dispersity drives column-to-column consistency and chromatographic performance. These associated gains in performance and reliability enable the development of high-throughput and high-resolution methods by simply implementing the right Kinetex core-shell particle for the application.
"The new Kinetex PS C18 and existing Kinetex Polar C18 are the optimal one-two punch for any polar/non-polar compound method development," explains Ryan Splitstone, Phenomenex LC Product Marketing Manager. "Their complementary mixed-mode selectivities and 100% aqueous stability add incredible versality to any HPLC or UHPLC instrumentation."
Combining the Kinetex core-shell 2.6 µm particle platform with the unique PS C18 selectivity affords scientists a high performance HPLC/UHPLC solution well suited for the analysis of different classes of acid, bases, and natural compounds under typical reversed phase conditions. Additionally, the Kinetex PS C18 selectivity is particularly applicable for the analysis of polar basic compounds that contain basic functionality and typically exhibit poor selectivity/peak performance on traditional C18 phases. While traditional alkyl C18 phases are prone to peak tailing issues for basic compounds due to uncontrolled secondary interactions occurring at the silica surface, the surface of the Kinetex PS C18 contains bonded positive charges that serves to repel basic species and deliver consistently sharper peak shape for basic compounds.
Learn more about the Kinetex Core-Shell HPLC/UHPLC product line at: www.phenomenex.com/Kinetex
Publish Date | Publication | Article Title |
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12/13/2019 | Cannabis testing: The need for robust methods and true transparency | |
05/08/2019 | Rapid Extraction and Analysis of PPCPs From Sediments |
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11/14/2018 | Chromatographic Analysis for PAT | |
11/12/2018 | High-Flow Weak Cation Exchange for Charge Variant Analysis | |
06/01/2018 | Bio-Inert versus Bio-Compatible: The Benefits of Different Column Materials in Liquid Chromatography... | |
02/23/2018 | Meeting the Demands of the Food Safety Laboratory Using Versatile Columns |
Publish Date | Publication | Article Title |
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07/18/2017 | SelectScience Interview: Improving Food Safety at the United States Department of Agriculture | |
06/20/2017 | Addressing the Challenges of Drug-to-Antibody Measurement | |
02/24/2017 | Dietary Supplements Method Modernization- A Review of Current Efforts to Modetnize Compendial Method... | |
02/14/2017 | How to Optimize Your Reversed Phase Chromatography |
Publish Date | Publication | Article Title |
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12/14/2016 | Customized Separation Solutions from PhenoLogix Experts | |
11/02/2016 | The Secrets Behind the Success of Phenomenex- Tips to the Top | |
10/06/2016 | The Phenomenex Story Part II: Leading the Field in Urine Analysis | |
09/27/2016 | Urinary Drug Testing: Small Changes for Big Improvements in Sensitivity | |
09/22/2016 | The Phenomenex Story Part I: The Architect Who Build a Chemistry Empire | |
07/6/2016 | Urine Analytics: The Good, The Bad, and The Ugly | |
07/20/2016 | Approaches to prescription opioid abuse testing |
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12/10/2015 | Allowable Adjustments to Pharmacopoeia Methods for Isocratic and Gradient Separations | |
10/1/2015 | New Approaches to Screening for Drug Abuse | |
04/09/2015 | Torrance Tribune - Crushing Malaria | |
03/03/2015 | Identifying the Increased Scope of Core-Shell Technology for HPLC and UHPLC Chromatographers |
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12/02/2014 | Eliminating Volumetric Haematocrit Bias Associated with DBS Sub-Punch Workflows Using a Novel Micros... |